The difference between them is really blurred." "Under some circumstances, the nonsedating formulas do cause sedation and in some cases, these sedating formulas do not," he tells Web MD.
"In some studies we reviewed, some people actually experienced more sedation with the newer, nonsedating formulas than with the older, sedating products.
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Most of the studies reviewed used doses that were twice the recommended amount -- 50 milligrams -- of diphenhydramine, the active ingredient in Benadryl and other first-generation "sedating" allergy medications.
Sedation is also used extensively in the intensive care unit so that patients who are being ventilated tolerate having an endotracheal tube in their trachea.
Sedation is typically used in minor surgical procedures such as endoscopy, vasectomy, or dentistry and for reconstructive surgery, some cosmetic surgeries, removal of wisdom teeth, or for high-anxiety patients.